Article
Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia.
Disease markers - 1 Jan 2018
Sakowicz Agata, Lisowska Michalina, Biesiada Lidia, Rybak-Krzyszkowska Magda, Gach Agnieszka, Sakowicz Bartosz, Grzesiak Mariusz, Huras Hubert, Pietrucha Tadeusz
Abstract excerpt
BACKGROUND: Metalloproteinases (MMPs) play a pivotal role during the process of trophoblast invasion and placentation. The appearance of five functional single-nucleotide polymorphisms (SNP) in the genes of the metalloproteinases most commonly implicated in the implantation process may influence the development of preeclampsia. METHODS: Blood samples were collected from 86 mothers and 86 children after...
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