Article
Genetic variation in matrix metalloproteinase MMP2 and MMP9 as a risk factor for idiopathic recurrent spontaneous abortions in an Indian population.
Journal of assisted reproduction and genetics - 1 Jul 2017
Ramu Deepika, Venkatesan Vettriselvi, Paul Solomon Franklin Durairaj, Koshy Teena
Abstract excerpt
PURPOSE: Matrix metalloproteinases, MMP2 and MMP9, are found to have an important role during ovulation and pregnancy because of their capacity to degrade components of the extracellular matrix (ECM) thereby facilitating cell migration and angiogenesis. In this respect, the aim of the present study was to evaluate the association of the promoter polymorphisms -1306 C > T and -1562 C/T in MMP2 and MMP9...
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