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Article

ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells.

Cancer letters - 28 Feb 2012

Krech Till, Scheuerer Elisa, Geffers Robert, Kreipe Hans, Lehmann Ulrich, Christgen Matthias

Abstract excerpt

Contribution of the ABCB1/MDR1/P-glycoprotein drug transporter to breast cancer resistance has been controversial. One issue is that ABCB1-dependent drug-resistance has primarily been investigated in mammary epithelial cell models technically manipulated to overexpress ABCB1, either by gene transfer using appropriate expression vectors or by chronic anticancer drug-selection. However, an unmodified human breast...

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Source

Identifiers

PMID: 22118813
DOI: 10.1016/j.canlet.2011.09.038

Genes

ABCB1
CCL28
PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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