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Article

ATP binding cassette transporters and drug resistance in breast cancer.

1 Mar 2003

Abstract excerpt

Resistance to chemotherapy is a critical issue in the management of breast cancer patients. The nature of clinical drug resistance is likely to be multifactorial. However, in the last decade considerable attention has been dedicated to the role played by membrane transporter proteins belonging to the ATP binding cassette protein superfamily, and in particular by the MDR1 product P-glycoprotein (Pgp) and the...

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Identifiers

PMID: 12653670
DOI: 10.1677/erc.0.0100043

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