Article
Breast cancer resistance protein (BCRP/ABCG2).
The international journal of biochemistry & cell biology - 1 Apr 2005
Staud Frantisek, Pavek Petr
Abstract excerpt
Breast cancer resistance protein (BCRP) was identified 7 years ago as the most recent member of ABC drug efflux membrane transporters. It is a 655 amino acid peptide with an ability to extrude a wide variety of chemical compounds from the cells. Today, it is considered as one of three major transporters causing drug resistance in mammalian cells. It is also distributed in epithelia involved in drug disposition...
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