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Article

Impact of breast cancer resistance protein on cancer treatment outcomes.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Ross Douglas D, Nakanishi Takeo

Abstract excerpt

Breast cancer resistance protein (BCRP/ABCG2) was discovered in multidrug resistant breast cancer cells having an ATP-dependent transport-based resistance phenotype. This ABC transporter functions (at least in part) as a xenobiotic protective mechanism for the organism: in the gut and biliary tract, it prevents absorption and enhances elimination of potentially toxic substances. As a placental barrier, it...

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Source

Identifiers

PMID: 19949928
DOI: 10.1007/978-1-60761-416-6_12

Genes

ABCB1
ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Impact of breast cancer resistance protein on cancer treatment outcomes.PMID 19949928Read ↗

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Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.Semantic proximity Read ↗

Structure and Function of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)Semantic proximity Read ↗

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ABC transporters in breast cancer: their roles in multidrug resistance and beyondSemantic proximity Read ↗

Drug transport by breast cancer resistance proteinSemantic proximity Read ↗

Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitorsSemantic proximity Read ↗

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