Article
Histologic variation among experimental tumors of common origin: relationships to viral p21 expression and to tumor-derived extracellular matrix.
International journal of cancer - 15 Oct 1990
Auersperg N, Wong A, MacLaren I A
Abstract excerpt
Transformed lines, obtained by infection of adult rat adrenocortical fibroblast-like cells with Kirsten murine sarcoma virus, produce s.c. tumors which range histologically from fibrosarcomas to carcinomas to undifferentiated neoplasms. This study was undertaken to determine whether the histology...
Topics
- Adrenal Glands
- Animals
- Biomarkers, Tumor
- Cell Differentiation
- Cell Line
- Cell Transformation, Neoplastic
- Collagen
- Electrophoresis, Polyacrylamide Gel
- Extracellular Matrix
- Gene Expression Regulation, Neoplastic
- Neoplasms, Experimental
- Oncogene Protein p21(ras)
- Phenotype
- Pregnenolone
- Rats
- Rats, Inbred F344