Article
Progression of hormone-dependent adenocarcinoma cells to hormone-independent spindle carcinoma cells in vitro in a clonal spontaneous rat mammary tumor cell line.
Cancer research - 15 Jan 1995
Nakanishi H, Taylor R M, Chrest F J, Masui T, Utsumi K, Tatematsu M, Passaniti A
Abstract excerpt
A hormone-dependent, clonal carcinoma cell line, designated RM22-F5, was derived from a malignant mammary mixed tumor spontaneously arising in an outbred old female Wistar rat. These cells expressed keratin and desmosomal protein and formed epithelial monolayers in a growth factor and hormone-sup...
Topics
- Adenocarcinoma
- Animals
- Base Sequence
- Carcinoma
- Cell Division
- Cell Fusion
- Cell Transformation, Neoplastic
- Culture Media
- Desmosomes
- Female
- Flow Cytometry
- Genes, ras
- Keratins
- Mammary Neoplasms, Animal
- Mice
- Mice, Nude
- Molecular Sequence Data
- Neomycin