Article
Rapid ras-oncogene-mediated transformation maintains steroidogenic differentiation in adrenocortical parenchymal cells.
Differentiation; research in biological diversity - 1 Sept 1995
Roskelley C D, Auersperg N
Abstract excerpt
While its action as a transforming agent is well known, expression of the ras oncogene may also alter tissue-specific differentiation. We have been examining the relationship of transformation and differentiation in steroidogenic cells of the rat. Infection of adrenocortical zona glomerulosa (GLO...
Topics
- Adrenal Cortex
- Adrenocorticotropic Hormone
- Animals
- Cell Differentiation
- Cell Transformation, Viral
- Cells, Cultured
- Cyclic AMP
- Genes, ras
- Kirsten murine sarcoma virus
- Male
- Phenotype
- Rats
- Rats, Inbred F344
- Steroids
- Zona Glomerulosa