Evaluating virus-transformed cell tumorigenicity.

doi:10.1016/s0166-0934(98)00182-7

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Article

Evaluating virus-transformed cell tumorigenicity.

Journal of virological methods - 1 Apr 1999

Lewis A M, Alling D W, Banks S M, Soddu S, Cook J L

Abstract excerpt

The tumorigenicity of adenovirus (Ad) 12-transformed mouse cells was evaluated by analyzing the relationship of tumor cell dose to tumor incidence and tumor latency. The tumor producing dose 50% endpoint values used to define these relationships remained stable during 52 weeks of serial passage in tissue culture and were not determined by low frequency events within the cell population. The data from these...

Topics

Adenoviridae
Animals
Cell Line, Transformed
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cell Transplantation
Cricetinae
Evaluation Studies as Topic
Mice
Mice, Inbred BALB C
Neoplasms, Experimental
Phenotype
Simian virus 40

Source

Open in PubMed

Identifiers

PMID: 10328534
DOI: 10.1016/s0166-0934(98)00182-7

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