Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DQ beta sequence polymorphism and genetic susceptibility to IDDM.

Diabetes - 1 Jan 1990

Erlich H A, Bugawan T L, Scharf S, Nepom G T, Tait B, Griffith R L

Abstract excerpt

The analysis of HLA-DQ beta nucleotide sequence polymorphism in insulin-dependent diabetes mellitus (IDDM) patients and control subjects suggests a role for the DQ beta-chain in genetic susceptibility. Sequence determination and oligonucleotide hybridization was carried out on enzymatically amplified DNA from various HLA-DR-typed individuals, including the rare class of DR2+ patients. In the analysis of DQ beta...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polymorphism, Genetic
Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Chromosome Mapping

Share to Genetic Predisposition to Disease

Share to Molecular Sequence Data

Source

Identifiers

PMID: 2210066
DOI: 10.2337/diacare.39.1.96

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DQ beta sequence polymorphism and genetic susceptibility to IDDM.PMID 2210066Read ↗

Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus.Semantic proximity Read ↗

HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

HLA class II sequences and genetic susceptibility to insulin dependent diabetes mellitus.Semantic proximity Read ↗

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Genetic analysis of HLA class II alleles and susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.Semantic proximity Read ↗

Analysis of HLA genotypes and susceptibility to insulin-dependent diabetes mellitus: HLA-DQ alpha complements HLA-DQ beta.Semantic proximity Read ↗

Aspartic acid at position 57 of the HLA-DQ beta chain in insulin-dependent diabetes mellitus: an association with one DRw9-DQw9 subtype in the Chinese population.Semantic proximity Read ↗

HLA-DQB1 alleles and absence of Asp 57 as susceptibility factors of IDDM in Finland.Semantic proximity Read ↗

Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain.Semantic proximity Read ↗

HLA-DQB1 codon 57 and IDDM in Chinese living in Taiwan.Semantic proximity Read ↗

Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes.Semantic proximity Read ↗

Heterogeneity of HLA genetic factors in IDDM susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.