Article
Aspartic acid at position 57 of the HLA-DQ beta chain in insulin-dependent diabetes mellitus: an association with one DRw9-DQw9 subtype in the Chinese population.
Tissue antigens - 1 May 1991
Ju L Y, Sun Y P, Semana G, Gu X F, Krishnamoorty R, Fauchet R, Charron D
Abstract excerpt
Eighteen unrelated Chinese patients with insulin-dependent diabetes mellitus (IDDM) were analyzed for HLA Class II genes using a variety of molecular biological techniques including restriction fragment length polymorphism (RFLP), polymerase chain reaction with allele-specific oligonucleotides (P...
Topics
- Alleles
- Asian People
- Aspartic Acid
- Base Sequence
- China
- DNA
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens
- HLA-DR Serological Subtypes
- Haplotypes
- Heterozygote
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction