Article
Polymorphisms in the human ALOX12 and ALOX15 genes are associated with peak bone mineral density in Chinese nuclear families.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jul 2012
Xiao W-J, Ke Y-H, He J-W, Zhang H, Yu J-B, Hu W-W, Gu J-M, Gao G, Yue H, Wang C, Hu Y-Q, Li M, Liu Y-J, Fu W-Z, Zhang Z-L
Abstract excerpt
SUMMARY: Association between ten single-nucleotide polymorphisms (SNPs) in the human ALOX12 and ALOX15 genes and variations in peak bone mineral density (BMD) in a large sample of Chinese nuclear families with female offspring using the quantitative transmission disequilibrium test (QTDT). Our results suggest that the genetic polymorphisms in both human ALOX12 and ALOX15 may contribute to variations in the peak...
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