Article
Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring.
Acta pharmacologica Sinica - 1 Feb 2012
Ke Yao-hua, Xiao Wen-jin, He Jin-wei, Zhang Hao, Yu Jin-bo, Hu Wei-wei, Gu Jie-mei, Gao Gao, Yue Hua, Wang Chun, Hu Yun-qiu, Li Miao, Liu Yu-juan, Fu Wen-zhen, Zhang Zhen-lin
Abstract excerpt
AIM: Genetic variation in ALOX12, which encoded human 12-lipoxygenase, was found to be associated with fat mass in young Chinese men. The objective of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs) and haplotypes in the ALOX15 gene and obesity-related phenotypes in Chinese nuclear families with male offspring. METHODS: We recruited 1,296 subjects from 427 nuclear...
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