Article
A differential association of ALOX15 polymorphisms with bone mineral density in pre- and post-menopausal women.
Human heredity - 1 Jan 2008
Cheung Ching-Lung, Chan Vivian, Kung Annie W C
Abstract excerpt
OBJECTIVE: The 12/15-lipoxygenase gene ALOX15 is reported to be a negative regulator of BMD in knockout mice. Nonetheless results are controversial as over-expression of ALOX15 protects against inflammation-related bone loss. The aim of the present study is to systematically study the relation of ALOX15 polymorphisms in BMD variation in southern Chinese women. METHODS: Ten tag single nucleotide polymorphisms...
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