Article
Association of low-density lipoprotein receptor-related protein 5 (LRP5) promoter SNP with peak bone mineral density in Chinese women.
Human heredity - 1 Jan 2008
Cheung Ching-Lung, Huang Qing-Yang, Chan Vivian, Kung Annie W C
Abstract excerpt
OBJECTIVE: Low-density lipoprotein receptor-related protein 5 (LRP5) is important for osteoblast differentiation and mutations of the gene are associated with both low and high bone mass syndromes. Our study aimed to evaluate the importance of LRP5 in the determination of peak bone mass acquisition in Chinese females in the general population. METHODS: A total of 286 young southern Chinese females (aged 22-44...
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