Article
No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families.
BMC medical genetics - 1 Jan 2010
Gao Gao, Zhang Zhen-Lin, He Jin-Wei, Zhang Hao, Yue Hua, Hu Wei-Wei, Gu Jie-Mei, Fu Wen-Zhen, Hu Yun-Qiu, Li Miao, Liu Yu-Juan, Yu Jin-Bo
Abstract excerpt
BACKGROUND: The Wnt/beta-catenin signaling pathway plays an important role in skeletal development. Polymorphisms of frizzled-related protein (FRZB), an antagonist of this pathway, may generate variations in bone mineral density (BMD). In this study, we analyzed the association between FRZB genot...
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