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Article

No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families.

BMC medical genetics - 1 Jan 2010

Gao Gao, Zhang Zhen-Lin, He Jin-Wei, Zhang Hao, Yue Hua, Hu Wei-Wei, Gu Jie-Mei, Fu Wen-Zhen, Hu Yun-Qiu, Li Miao, Liu Yu-Juan, Yu Jin-Bo

Abstract excerpt

BACKGROUND: The Wnt/beta-catenin signaling pathway plays an important role in skeletal development. Polymorphisms of frizzled-related protein (FRZB), an antagonist of this pathway, may generate variations in bone mineral density (BMD). In this study, we analyzed the association between FRZB genotypes and peak BMD variation in the spines and hips of two relatively large samples of Chinese female-offspring and...

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Identifiers

PMID: 20043861
DOI: 10.1186/1471-2350-11-1
PMCID: PMC2806249

Genes

FRZB

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Source receipt: pubmed, retrieved 7 Sept 2026.

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