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Article

ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families.

International journal of obesity (2005) - 1 Mar 2011

Xiao W-J, He J-W, Zhang H, Hu W-W, Gu J-M, Yue H, Gao G, Yu J-B, Wang C, Ke Y-H, Fu W-Z, Zhang Z-L

Abstract excerpt

OBJECTIVE: Arachidonate 12-lipoxygenase (ALOX12) is a member of the lipoxygenase superfamily, which catalyzes the incorporation of molecular oxygen into polyunsaturated fatty acids. The products of ALOX12 reactions serve as endogenous ligands for peroxisome proliferator-activated receptor γ (PPARG). The activation of the PPARG pathway in marrow-derived mesenchymal progenitors stimulates adipogenesis and inhibits...

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Source

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Identifiers

PMID: 20697415
DOI: 10.1038/ijo.2010.157
PMCID: PMC3061002

Genes

ALOX12
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families.PMID 20697415Read ↗

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