Article
Kinetic modelling of DNA replication initiation in budding yeast.
Genome informatics. International Conference on Genome Informatics - 1 Jan 2010
Barberis Matteo, Spiesser Thomas W, Klipp Edda
Abstract excerpt
DNA replication is restricted to a specific time window of the cell cycle, called S phase. Successful progression through S phase requires replication to be properly regulated to ensure that the entire genome is duplicated exactly once, without errors, in a timely fashion. As a result, DNA replication has evolved into a tightly regulated process involving the coordinated action of numerous factors that function...
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