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Article

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms.

Nature - 28 Jun 2001

Nguyen V Q, Co C, Li J J

Abstract excerpt

The stable propagation of genetic information requires that the entire genome of an organism be faithfully replicated once and only once each cell cycle. In eukaryotes, this replication is initiated at hundreds to thousands of replication origins distributed over the genome, each of which must be prohibited from re-initiating DNA replication within every cell cycle. How cells prevent re-initiation has been a...

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Identifiers

PMID: 11429609
DOI: 10.1038/35082600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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