Advanced light-entrained activity onsets and restored free-running suprachiasmatic nucleus circadian rhythms in per2/dec mutant mice.

doi:10.3109/07420528.2011.607374

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Article

Advanced light-entrained activity onsets and restored free-running suprachiasmatic nucleus circadian rhythms in per2/dec mutant mice.

Chronobiology international - 1 Nov 2011

Bode Brid, Taneja Reshma, Rossner Moritz J, Oster Henrik

Abstract excerpt

Many behavioral and physiological processes display diurnal (24-h) rhythms controlled by an internal timekeeping system?the circadian clock. In mammals, a circadian pacemaker is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and synchronizes peripheral oscillators found in most other tissues with the external light-dark (LD) cycle. At the molecular level, circadian clocks are regulated by...

Topics

Activity Cycles
Animals
Basic Helix-Loop-Helix Transcription Factors
Circadian Rhythm
Feedback, Physiological
Homeodomain Proteins
In Situ Hybridization
Locomotion
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Knockout

Mice, Mutant Strains

Motor Activity

Mutation

Period Circadian Proteins

Photoperiod

Suprachiasmatic Nucleus

Source

Open in PubMed

Identifiers

PMID: 22080784
DOI: 10.3109/07420528.2011.607374

Genes

TTL
BHLHE40
BHLHE41
BMAL1
CLOCK
NPAS2
PER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22080784-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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