Article
Molecular components of the mammalian circadian clock.
Human molecular genetics - 15 Oct 2006
Ko Caroline H, Takahashi Joseph S
Abstract excerpt
Circadian rhythms are approximately 24-h oscillations in behavior and physiology, which are internally generated and function to anticipate the environmental changes associated with the solar day. A conserved transcriptional-translational autoregulatory loop generates molecular oscillations of 'clock genes' at the cellular level. In mammals, the circadian system is organized in a hierarchical manner, in which a...
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