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Natural killer cell engineering for cellular therapy of cancer

13 Nov 2011

Abstract excerpt

Natural killer (NK) cells can kill transformed cells and represent a promising tool for the treatment of cancer. Their function is governed by a balance of stimulatory and inhibitory signals triggered by surface receptors. Advances in NK cell therapy require the development of dependable methods for obtaining an adequate number of effector cells; additional activation or genetic modification may further increase...

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PMID: 22077621
DOI: 10.1111/j.1399-0039.2011.01796.x

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