Article

Natural Born Killers: NK Cells in Cancer Therapy

2020-07-07

Abstract excerpt

Cellular therapy has emerged as an attractive option for the treatment of cancer, and adoptive transfer of chimeric antigen receptor (CAR) expressing T cells has gained FDA approval in hematologic malignancy. However, limited efficacy has been observed utilizing CAR-T therapy in solid tumors. Natural killer (NK) cells are crucial for tumor surveillance and exhibit potent killing capacity of aberrant cells in an an...

Identifiers and source

Literature Corpus work: 8497cdd0-e8fa-5442-aa3a-680b6ae5a196
DOI: 10.20944/preprints202007.0139.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Natural Born Killers: NK Cells in Cancer TherapyDOI 10.20944/preprints202007.0139.v1Read

NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful DevelopmentSemantic proximity Read

Advantages and clinical applications of natural killer cells in cancer immunotherapy.Semantic proximity Read

Natural killer cell therapy for hematologic malignancies: successes, challenges, and the futureSemantic proximity Read

Dark NKnight rising: a current perspective on NK cell and CAR-NK cell therapySemantic proximity Read

Natural killer cell‐based immunotherapy in cancer: current insights and future prospectsSemantic proximity Read

Chimeric antigen receptor-natural killer cell therapy: current advancements and strategies to overcome challengesSemantic proximity Read

A structural, genetic and clinical comparison of CAR-T cells and CAR-NK cells: companions or competitors?Semantic proximity Read

Chimeric antigen receptor-natural killer cell therapy: a new force in intrinsic immunotherapy for cancer treatmentSemantic proximity Read

Natural killer cell engineering for cellular therapy of cancerSemantic proximity Read

Human NK cells and cancerSemantic proximity Read

High-Risk Leukemia: Past, Present, and Future Role of NK CellsSemantic proximity Read

The Natural Killer Cell Line NK-92 and Its Genetic Variants: Impact on NK Cell Research and Cancer ImmunotherapySemantic proximity Read