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Nonviral genome engineering of natural killer cells

16 Jun 2021

Abstract excerpt

Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system capable of immune surveillance. Given their ability to rapidly and effectively recognize and kill aberrant cells, especially transformed cells, NK cells represent a unique cell type to genetically engineer to improve its potential as a cell-based therapy. NK cells do not express a T cell receptor and thus do not contribute to...

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PMID: 34134774
DOI: 10.1186/s13287-021-02406-6

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