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Article

The FGF and FGFR Gene Family and Risk of Cleft Lip With or Without Cleft Palate.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jan 2013

Wang Hong, Zhang Tianxiao, Wu Tao, Hetmanski Jacqueline B, Ruczinski Ingo, Schwender Holger, Liang Kung Yee, Murray Tanda, Fallin M Daniele, Redett Richard J, Raymond Gerald V, Jin Sheng-Chih, Chou Yah-Huei Wu, Chen Philip Kuo-Ting, Yeow Vincent, Chong Samuel S, Cheah Felicia S H, Jee Sun Ha, Jabs Ethylin W, Scott Alan F, Beaty Terri H

Abstract excerpt

Background : Isolated, nonsyndromic cleft lip with or without cleft palate is a common human congenital malformation with a complex and heterogeneous etiology. Genes coding for fibroblast growth factors and their receptors (FGF/FGFR genes) are excellent candidate genes. Methods : We tested single-nucleotide polymorphic markers in 10 FGF/FGFR genes (including FGFBP1, FGF2, FGF10, FGF18, FGFR1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22074045
DOI: 10.1597/11-132
PMCID: PMC3387510

Genes

FGF19
FGFR1
FGF10
FGF18
FGF2
FGF9
FGFR2
FGF3
FGF4
FGFBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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