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Article

A Population-Based Study of Effects of Genetic Loci on Orofacial Clefts.

Journal of dental research - 1 Oct 2017

Moreno Uribe L M, Fomina T, Munger R G, Romitti P A, Jenkins M M, Gjessing H K, Gjerdevik M, Christensen K, Wilcox A J, Murray J C, Lie R T, Wehby G L

Abstract excerpt

Prior genome-wide association studies for oral clefts have focused on clinic-based samples with unclear generalizability. Prior samples were also small for investigating effects by cleft type and exclusively studied isolated clefts (those occurring without other birth defects). We estimated the effects of 17 top loci on cleft types in both isolated and nonisolated cases in the largest consortium to date of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28662356
DOI: 10.1177/0022034517716914
PMCID: PMC5607104

Genes

ABCA4
ARHGAP29
FOXE1
MAFB
PAX7
SPRY2
TPM1
VAX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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