Article
Investigation of FGF1 and FGFR gene polymorphisms in a group of Iranian patients with nonsyndromic cleft lip with or without cleft palate.
International journal of pediatric otorhinolaryngology - 1 May 2014
Rafiqdoost Zahra, Rafiqdoost Amir, Rafiqdoost Houshang, Hashemi Mohammad, Khayatzadeh Jina, Eskandari-Nasab Ebrahim
Abstract excerpt
OBJECTIVE: Nonsyndromic cleft lip with or without cleft palate (NS-CL/P) is one of the most common craniofacial malformations determined by the interaction between multiple genes and environmental risk factors. Genes coding for fibroblast growth factors and their receptors (FGF/FGFR genes) are considered as excellent candidate genes, which their proteins play important roles in craniofacial and palatal...
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