Article
Variation in FGF1, FOXE1, and TIMP2 genes is associated with nonsyndromic cleft lip with or without cleft palate.
Birth defects research. Part A, Clinical and molecular teratology - 1 Apr 2011
Nikopensius Tiit, Kempa Inga, Ambrozaitytė Laima, Jagomägi Triin, Saag Mare, Matulevičienė Aušra, Utkus Algirdas, Krjutškov Kaarel, Tammekivi Veronika, Piekuse Linda, Akota Ilze, Barkane Biruta, Krumina Astrida, Klovins Janis, Lace Baiba, Kučinskas Vaidutis, Metspalu Andres
Abstract excerpt
BACKGROUND: Nonsyndromic cleft lip with or without cleft palate (CL/P) is a common complex birth defect caused by the interaction between multiple genes and environmental factors. METHODS: Five hundred and eighty-seven single nucleotide polymorphisms in 40 candidate genes related to orofacial clefting were tested for association with CL/P in a clefting sample composed of 300 patients and 606 controls from...
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