Article
The interaction between aminoacyl-tRNA and the mutant elongation factors Tu AR and B0.
Biochimica et biophysica acta - 27 Aug 1990
Abrahams J P, Acampo J J, Ott G, Sprinzl M, de Graaf J M, Talens A, Kraal B
Abstract excerpt
The binding of Tyr-[AEDANS-s2C]tRNA(Tyr) (Tyr-tRNA(Tyr) modified at the penultimate cytidine residue with a thio group at position 2 of the pyrimidine ring, to which an N-(acetylaminoethyl)-5-naphthylamine-1-sulfonic acid fluorescence group is attached) to mutant elongation factor (EF)-Tu species...
Topics
- Anti-Bacterial Agents
- Escherichia coli
- Fluorescent Dyes
- Guanosine Diphosphate
- Guanosine Triphosphate
- Kinetics
- Mutation
- Naphthalenesulfonates
- Peptide Elongation Factor Tu
- Pyridones
- RNA, Transfer, Tyr
- Structure-Activity Relationship
- Sulfhydryl Compounds