Article
Antisuppression by mutations in elongation factor Tu.
European journal of biochemistry - 10 Mar 1990
Tapio S, Isaksson L A
Abstract excerpt
Two slow-growing kirromycin-resistant Escherichia coli mutants with altered EF-Tu (Ap and Aa) were studied in vivo in strains with an inactive tufB gene. Mutant form Aa was isolated as an antisuppressor of the tyrT(Su3) nonsense suppressor, as described here. Ap, the tufA gene product of strain D2216 (from A. Parmeggiani), has previously been shown to give an increased GTPase activity. The slow cellular growth...
Topics
- Amino Acids
- Codon
- Escherichia coli
- Lac Operon
- Peptide Elongation Factor Tu
- Phenotype
- Protein Biosynthesis
- RNA, Ribosomal
- RNA, Transfer
- Suppression, Genetic
- Temperature