Article
Morphological and Functional Evaluation of Axons and their Synapses during Axon Death in Drosophila melanogaster.
Journal of visualized experiments : JoVE - 16 Mar 2020
Paglione Maria, Rosell Arnau Llobet, Chatton Jean-Yves, Neukomm Lukas J
Abstract excerpt
Axon degeneration is a shared feature in neurodegenerative disease and when nervous systems are challenged by mechanical or chemical forces. However, our understanding of the molecular mechanisms underlying axon degeneration remains limited. Injury-induced axon degeneration serves as a simple model to study how severed axons execute their own disassembly (axon death). Over recent years, an evolutionarily...
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