Article
TP53 codon 72 polymorphisms in favorable histology Wilms tumors.
Pediatric blood & cancer - 1 Aug 2012
Cost Nicholas G, Mitui Midori, Khokhar Shama, Wickiser Jonathan E, Baker Linda A, Rakheja Dinesh
Abstract excerpt
In Wilms tumor (WT), mutations in the gene encoding p53, TP53, are correlated with anaplasia; however TP53 variants have not been studied in favorable histology (FH) WTs. A single nucleotide polymorphism of TP53 encoding either arginine or proline at codon 72 is suggested to alter in vitro p53 be...
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