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Article

Possible association of p53 codon 72 polymorphism with susceptibility to adult and pediatric high-grade astrocytomas.

Brain research. Molecular brain research - 13 Jun 2005

Parhar Preeti, Ezer Rona, Shao Yongzhao, Allen Jeffrey C, Miller Douglas C, Newcomb Elizabeth W

Abstract excerpt

Polymorphisms in codon 72 of the p53 tumor suppressor gene have been associated with susceptibility to human cancer. We wished to evaluate whether variant allelic forms of the p53 protein were associated with brain tumors. In this study, we scored 135 brain tumor samples (92 adult and 43 pediatric cases consisting of 64 high-grade astrocytomas and 71 non-astrocytomas) for the P53 Arg72Pro polymorphisms. Our data...

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Identifiers

PMID: 15950766
DOI: 10.1016/j.molbrainres.2005.02.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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