Article
TP53 codon 72 polymorphism in adult soft tissue sarcomas.
Genetics and molecular research : GMR - 1 Jan 2008
Almeida P S R, Manoel W J, Reis A A S, Silva E R, Martins E, Paiva M V O, Fraga A C, Saddi V A
Abstract excerpt
Soft tissue sarcomas (STS) are tumors of mesodermal origin, comprising about 1% of all adult neoplasms. Management of such tumors is an important medical challenge. TP53 codon 72 polymorphism results in either the arginine or proline form of the p53 protein; several studies have investigated whether codon 72 polymorphisms are risk and prognostic factors for cancer. We investigated p53 codon 72 polymorphism...
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