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Article

Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features.

Current neurovascular research - 1 Jan 2021

Ozsoy Filiz, Nursal Ayse F, Karakus Nevin, Demir Meral O, Yigit Serbulent

Abstract excerpt

OBJECTIVE: Major Depressive Disorder (MDD) is a major health problem worldwide. Estrogen interacts with the central nervous system and has been shown to affect anxiety and depressive behavior. Estrogen mediates its effects by connecting its receptors, estrogen receptors 1 and 2. The purpose of this case-control study was to clarify the association between MDD risk and estrogen receptor 1 (ESR1) gene variants....

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PMID: 34060989
DOI: 10.2174/1567202618666210531122239

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