Article
Oestrogen receptor polymorphisms and late-life depression.
The British journal of psychiatry : the journal of mental science - 1 Aug 2011
Ryan Joanne, Scali Jacqueline, Carrière Isabelle, Peres Karine, Rouaud Olivier, Scarabin Pierre-Yves, Ritchie Karen, Ancelin Marie-Laure
Abstract excerpt
BACKGROUND: Evidence suggests a role for oestrogen in depression but the involvement of oestrogen receptor polymorphisms remains unknown. AIMS: To determine the association between oestrogen receptor polymorphisms and late-life depression and the modifying effect of hormone treatment. METHOD: Depression was assessed using the Mini-International Neuropsychiatric Interview, according to DSM-IV criteria and the...
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