Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex-Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome-Wide Association Study of All of Us and UK Biobank Data.

Genetic epidemiology - 1 Apr 2025

Hu Yue, Che Menglu, Zhang Heping

Abstract excerpt

Major depressive disorder (MDD) is prevalent worldwide, substantially and negatively impacting both the quality and length of life of 280 million people globally. The genetic risk factors of MDD have been studied in various previous research, but the findings lack consistency. Sex/gender and racial/ethnic disparities have been reported; however, many previous genetic studies, represented by large-scale...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Specimen Banks
Share to Estrogen Receptor alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Major Depressive Disorder

Share to Sex Factors

Share to UK Biobank

Share to United Kingdom

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 40007508
DOI: 10.1002/gepi.70004
PMCID: PMC11924109

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex-Specific Association Between Polymorphisms in Estrogen Receptor Alpha Gene (ESR1) and Depression: A Genome-Wide Association Study of All of Us and UK Biobank Data.PMID 40007508Read ↗

Sex steroid hormone gene polymorphisms and depressive symptoms in women at midlife.Semantic proximity Read ↗

Association study of the estrogen receptor alpha gene (ESR1) and childhood-onset mood disorders.Semantic proximity Read ↗

Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features.Semantic proximity Read ↗

A sex-specific genome-wide association study of depression phenotypes in UK Biobank.Semantic proximity Read ↗

A Sex-Specific Genome-Wide Association Study of Depression Phenotypes in UK BiobankSemantic proximity Read ↗

Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples.Semantic proximity Read ↗

The role of allelic variation in estrogen receptor genes and major depression in the Nurses Health Study.Semantic proximity Read ↗

Association study of the estrogen receptor gene ESR1 with postpartum depression--a pilot study.Semantic proximity Read ↗

Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha gene.Semantic proximity Read ↗

Sex-specific transcriptional signatures in human depressionSemantic proximity Read ↗

Estrogen receptor alpha gene variants and major depressive episodes.Semantic proximity Read ↗

Sex differences in the genetic architecture of depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.