Article
[Application of High-throughput Sequencing in Acute Myeloid Leukemia Patients with Positive FLT3-ITD].
Zhongguo shi yan xue ye xue za zhi - 1 Apr 2016
Ma Liang, Jiang Yong-Wei, Wang Shao-Ting, Liu Qian, Cong Xiao, Shen Jun, Cao Yong-Yue, Cao Yong-Tong
Abstract excerpt
UNLABELLED: OBJECTICE: To evaluate the application of high-throughput sequencing to sequence the FMS-like Tyrosine Kinase 3 internal tandem duplication (FLT3-ITD) in de novo acute myeloid leukemia (AML) patients with lower allelic ratio FLT3-ITD mutation or more than one ITD, and to analyze the feature of ITD. METHODS: The genomic DNA of 23 AML patients with positive FLT3-ITD was amplified by PCR, capillary...
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