Article
[ITD mutation burden for the prognosis in FLT3-ITD positive acute myeloid leukemia patients].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Jun 2015
Ding Shasha, Shen Hongjie, Chen Zixing, Chen Suning, Cen Jiannong, Ding Zixuan, He Jun
Abstract excerpt
OBJECTIVE: To explore the impact of ITD mutation characteristics on the overall survival (OS) and complete remission duration (CRD) in FLT3-ITD positive non-M3 acute myeloid leukemia (AML). METHODS: Capillary electrophoresis was used to detect the FLT3-ITD characteristics after PCR amplication. Single or multiple mutations were identified by the numbers of peak. FLT3-ITD mutation burden was calculated by the peak...
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