Article
A semi-empirical approach for predicting unobserved peptide MS/MS spectra from spectral libraries.
Proteomics - 1 Dec 2011
Hu Yingwei, Li Yunzi, Lam Henry
Abstract excerpt
Spectral library searching is a promising alternative to sequence database searching in peptide identification from MS/MS spectra. The key advantage of spectral library searching is the utilization of more spectral features to improve score discrimination between good and bad matches, and hence sensitivity. However, the coverage of reference spectral library is limited by current experimental and computational...
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