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sapFinder: an R/Bioconductor package for detection of variant peptides in shotgun proteomics experiments.

Bioinformatics (Oxford, England) - 1 Nov 2014

Wen Bo, Xu Shaohang, Sheynkman Gloria M, Feng Qiang, Lin Liang, Wang Quanhui, Xu Xun, Wang Jun, Liu Siqi

Abstract excerpt

UNLABELLED: Single nucleotide variations (SNVs) located within a reading frame can result in single amino acid polymorphisms (SAPs), leading to alteration of the corresponding amino acid sequence as well as function of a protein. Accurate detection of SAPs is an important issue in proteomic analysis at the experimental and bioinformatic level. Herein, we present sapFinder, an R software package, for detection of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25053745
DOI: 10.1093/bioinformatics/btu397
PMCID: PMC4609003

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