Article

SpecGlob: rapid and accurate alignment of mass spectra differing from their peptide models by several unknown modifications

2022-05-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In proteomics, mass spectra representing peptides carrying multiple unknown modifications are particularly difficult to interpret, which results in a large number of unidentified spectra. <h4>Methods</h4> We developed SpecGlob, a dynamic programming algorithm that aligns pairs of spectra, each such pair being a Peptide-Spectrum Match (PSM) provided by any Open Modification...

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Literature Corpus work: 8bfd5967-5759-5a29-9854-2571b4a73ebc
DOI: 10.1101/2022.05.31.494131

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