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Article

Efficiency of database search for identification of mutated and modified proteins via mass spectrometry.

Genome research - 1 Feb 2001

Pevzner P A, Mulyukov Z, Dancik V, Tang C L

Abstract excerpt

Although protein identification by matching tandem mass spectra (MS/MS) against protein databases is a widespread tool in mass spectrometry, the question about reliability of such searches remains open. Absence of rigorous significance scores in MS/MS database search makes it difficult to discard random database hits and may lead to erroneous protein identification, particularly in the case of mutated or...

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Identifiers

PMID: 11157792
DOI: 10.1101/gr.154101
PMCID: PMC544186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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