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Article

Analysis of the resolution limitations of peptide identification algorithms.

Journal of proteome research - 2 Dec 2011

Colaert Niklaas, Degroeve Sven, Helsens Kenny, Martens Lennart

Abstract excerpt

Proteome identification using peptide-centric proteomics techniques is a routinely used analysis technique. One of the most powerful and popular methods for the identification of peptides from MS/MS spectra is protein database matching using search engines. Significance thresholding through false discovery rate (FDR) estimation by target/decoy searches is used to ensure the retention of predominantly confident...

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PMID: 21995378
DOI: 10.1021/pr200913a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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