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Article

Ahnak1 is a tuneable modulator of cardiac Ca(v)1.2 calcium channel activity.

Journal of muscle research and cell motility - 1 Dec 2011

Pankonien Ines, Alvarez Julio L, Doller Anke, Köhncke Clemens, Rotte Dana, Regitz-Zagrosek Vera, Morano Ingo, Haase Hannelore

Abstract excerpt

Ahnak1 has been implicated in the beta-adrenergic regulation of the cardiac L-type Ca(2+) channel current (I (CaL)) by its binding to the regulatory Cavβ(2) subunit. In this study, we addressed the question whether ahnak1/Cavβ(2) interactions are essential or redundant for beta-adrenergic stimulation of I (CaL). Three naturally occurring ahnak1 variants (V5075 M,...

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Source

Identifiers

PMID: 22038483
DOI: 10.1007/s10974-011-9269-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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