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Article

Ahnak is critical for cardiac Ca(V)1.2 calcium channel function and its beta-adrenergic regulation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2005

Haase Hannelore, Alvarez Julio, Petzhold Daria, Doller Anke, Behlke Joachim, Erdmann Jeanette, Hetzer Roland, Regitz-Zagrosek Vera, Vassort Guy, Morano Ingo

Abstract excerpt

Defective L-type Ca2+ channel (I(CaL)) regulation is one major cause for contractile dysfunction in the heart. The I(CaL) is enhanced by sympathetic nervous stimulation: via the activation of beta-adrenergic receptors, PKA phosphorylates the alpha1C(Ca(V)1.2)- and beta2-channel subunits and ahnak...

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Identifiers

PMID: 16319140
DOI: 10.1096/fj.05-3997com

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16319140-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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