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Article

Polymorphisms in cycloxygenase-2 gene and breast cancer prognosis: association between PTGS2 haplotypes and histopathological features.

Breast cancer research and treatment - 1 Feb 2012

Festa-Vasconcellos Juliana S, Piranda Diogo N, Amaral Laura M, Indio-do-Brasil Vanessa, Koifman Sérgio, Vianna-Jorge Rosane

Abstract excerpt

Cyclooxygenase-2 (COX-2) overexpression is associated with worse prognosis in breast cancer. COX-2 is encoded by a polymorphic gene, called PTGS2, and its expression may be genetically influenced. In this article, we investigate the association between PTGS2 haplotypes and histopathological parameters with prognostic value on the clinical outcome of breast cancer. The study involved 606 women under current...

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Source

Identifiers

PMID: 22037828
DOI: 10.1007/s10549-011-1828-0

Genes

PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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