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Article

Polymorphisms in regulatory regions of cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study.

BMC cancer - 8 Nov 2010

Piranda Diogo N, Festa-Vasconcellos Juliana S, Amaral Laura M, Bergmann Anke, Vianna-Jorge Rosane

Abstract excerpt

BACKGROUND: Cyclooxygenase-2 (COX-2) is up-regulated in several types of cancer, and it is hypothesized that COX-2 expression may be genetically influenced. Here, we evaluate the association between single-nucleotide polymorphisms (SNPs) in the COX-2 gene (PTGS2) and the occurrence of breast cancer among Brazilian women. METHODS: The study was conducted prospectively in two steps: First, we screened the promoter...

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Source

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Identifiers

PMID: 21059239
DOI: 10.1186/1471-2407-10-613
PMCID: PMC2992523

Genes

PTGS2
MAF

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Polymorphisms in regulatory regions of cyclooxygenase-2 gene and breast cancer risk in Brazilians: a case-control study.PMID 21059239Read ↗

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