Article
Cyclooxygenase-2 polymorphisms and breast cancer associated risk in Pakistani patients.
Pathology oncology research : POR - 1 Jan 2015
Moatter Tariq, Aban Muniba, Iqbal Waseem, Pervez Shahid
Abstract excerpt
UNLABELLED: Prostaglandins produced by Cyclooxygenase-2 enzyme have been implicated to have a role in breast carcinogenesis. Several single nucleotide polymorphisms (SNPs) linked to COX-2 enzyme are reported to modulate its expression. The aim of the present study was to examine association of these SNPs to breast cancer risk in Pakistani patients. METHODS: In this case-control study, three sequence variants...
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